PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

Tumor recurrence versus treatment effects in glioma: A comparative study of three dimensional pseudo-continuous arterial spin labeling and dynamic susceptibility contrast imaging.

Abstract Gliomas constitute over 90% of primary brain tumors. Accurate identification of glioma recurrence and treatment effects is important, as it can help determine whether to continue with standard adjuvant chemotherapy or to switch to a second-line therapy for recurrence. Our purpose is to compare three dimensional pseudo-continuous arterial spin labeling (3D-pcASL) technique and dynamic susceptibility contrast perfusion magnetic resonance imaging (DSC-MRI) for differentiation tumor recurrence from treatment-related effects in gliomas.
PMID
Related Publications

Comparative evaluation of 3-dimensional pseudocontinuous arterial spin labeling with dynamic contrast-enhanced perfusion magnetic resonance imaging in grading of human glioma.

Perfusion MRI (dynamic susceptibility contrast imaging) with different measurement approaches for the evaluation of blood flow and blood volume in human gliomas.

Prognostic value of blood flow estimated by arterial spin labeling and dynamic susceptibility contrast-enhanced MR imaging in high-grade gliomas.

Three-dimensional arterial spin labeling imaging and dynamic susceptibility contrast perfusion-weighted imaging value in diagnosing glioma grade prior to surgery.

Assesment of perfusion in glial tumors with arterial spin labeling; comparison with dynamic susceptibility contrast method.

Authors

Mayor MeshTerms
Keywords
Journal Title medicine
Publication Year Start




PMID- 29390403
OWN - NLM
STAT- MEDLINE
DCOM- 20180212
LR  - 20180212
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 96
IP  - 50
DP  - 2017 Dec
TI  - Tumor recurrence versus treatment effects in glioma: A comparative study of three
      dimensional pseudo-continuous arterial spin labeling and dynamic susceptibility
      contrast imaging.
PG  - e9332
LID - 10.1097/MD.0000000000009332 [doi]
AB  - BACKGROUND: Gliomas constitute over 90% of primary brain tumors. Accurate
      identification of glioma recurrence and treatment effects is important, as it can
      help determine whether to continue with standard adjuvant chemotherapy or to
      switch to a second-line therapy for recurrence. Our purpose is to compare three
      dimensional pseudo-continuous arterial spin labeling (3D-pcASL) technique and
      dynamic susceptibility contrast perfusion magnetic resonance imaging (DSC-MRI)
      for differentiation tumor recurrence from treatment-related effects in gliomas.
      METHODS: Twenty-nine patients with gliomas previously who showed enlarged,
      contrast-enhancing lesions within the radiation field after surgery and
      concurrent chemoradiotherapy (CCRT) were assessed with 3D-pcASL and DSC-MRI.
      These patients were classified into 2 groups, tumor recurrence group (n = 17) and
      treatment effects group (n = 12), based on pathologic analysis or
      clinical-radiologic follow-up. The perfusion imaging quality was assessed using a
      3-point scale (1 = poor imaging, 2 = moderate imaging, and 3 = good imaging).
      Comparison for perfusion imaging-quality score between the 2 techniques was
      performed with Wilcoxon one-sample test. Quantitative analyses were performed
      between the 2 groups with cerebral blood flow values (ASL-CBF), relative cerebral
      blood flow values (ASL-rCBF, DSC-rCBF), and relative cerebral blood volume values
      (DSC-rCBV) using Wilcoxon one-sample test. The intra-class correlation
      coefficient (ICC) statistics were calculated for testing intrareader variability 
      in regions of interest (ROIs) measurement of all perfusion parameters. RESULTS:
      The imaging-quality score of 3D-pcASL was higher than that of DSC-MRI (P = .01). 
      The perfusion parameters between tumor recurrence group and treatment effects
      group had statistically significant differences. There was a significant
      correlation between ASL-rCBF and DSC-rCBF values (r = 0.803), between ASL-rCBF
      and DSC-rCBV values (r = 0.763), and between DSC-rCBF and DSC-rCBV (r = 0.907). A
      receiver operating characteristic (ROC) curve analysis was performed for
      significant results of perfusion parameters between the 2 groups. Using a cutoff 
      value of 1.110, ASL-rCBF showed the maximum area under the ROC curve (AUC).
      However, there were no significant differences among different AUCs. The ICC
      demonstrated excellent agreement for ROIs measurements of ASL-CBF (ICC = 0.9636),
      dynamic susceptibility contrast- cerebral blood flow (DSC-CBF) (ICC = 0.8508),
      and dynamic susceptibility contrast-cerebral blood volume (DSC-CBV) (ICC =
      0.8543). CONCLUSION: 3D-pcASL is an alternative perfusion method to DSC-MRI for
      the differentiation between tumor recurrence and treatment effects in gliomas.
      3D-pcASL is noninvasive and shows fewer susceptibility artifacts than DSC-MRI.
CI  - Copyright (c) 2017 The Authors. Published by Wolters Kluwer Health, Inc. All
      rights reserved.
FAU - Xu, Qian
AU  - Xu Q
AD  - The First School of Clinical Medicine, Nanjing Medical University.
AD  - Department of Radiology, Affiliated Hospital of Xuzhou Medical University.
FAU - Liu, Qi
AU  - Liu Q
AD  - Department of Radiology, Affiliated Hospital of Xuzhou Medical University.
FAU - Ge, Haitao
AU  - Ge H
AD  - Department of Medical Imaging, Xuzhou Medical University.
FAU - Ge, Xinting
AU  - Ge X
AD  - Department of Medical Imaging, Xuzhou Medical University.
FAU - Wu, Jiangfen
AU  - Wu J
AD  - GE Healthcare, Shanghai, China.
FAU - Qu, Jianxun
AU  - Qu J
AD  - GE Healthcare, Shanghai, China.
FAU - Xu, Kai
AU  - Xu K
AD  - The First School of Clinical Medicine, Nanjing Medical University.
AD  - Department of Radiology, Affiliated Hospital of Xuzhou Medical University.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 0 (Contrast Media)
RN  - 0 (Spin Labels)
SB  - AIM
SB  - IM
MH  - Artifacts
MH  - Brain Neoplasms/*diagnostic imaging/*pathology/surgery
MH  - Cerebrovascular Circulation
MH  - Contrast Media
MH  - Female
MH  - Glioma/*diagnostic imaging/*pathology/surgery
MH  - Humans
MH  - Magnetic Resonance Angiography/*methods
MH  - Male
MH  - Middle Aged
MH  - Neoplasm Recurrence, Local/*diagnostic imaging/*pathology
MH  - Prospective Studies
MH  - Spin Labels
EDAT- 2018/02/03 06:00
MHDA- 2018/02/13 06:00
CRDT- 2018/02/03 06:00
PHST- 2018/02/03 06:00 [entrez]
PHST- 2018/02/03 06:00 [pubmed]
PHST- 2018/02/13 06:00 [medline]
AID - 10.1097/MD.0000000000009332 [doi]
AID - 00005792-201712150-00153 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2017 Dec;96(50):e9332. doi: 10.1097/MD.0000000000009332.