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Asymptomatic solitary bladder plasmocytoma: A case report and literature review.

Abstract Solitary extramedullary plasmocytoma may arise in any organ, either as a primary tumor or as part of a systemic myeloma; if it rarely affects bladder, it presents with urinary symptoms. We describe the first case of asymptomatic BP occasionally diagnosed in a patient with ascites.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title medicine
Publication Year Start




PMID- 29390408
OWN - NLM
STAT- MEDLINE
DCOM- 20180212
LR  - 20180212
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 96
IP  - 50
DP  - 2017 Dec
TI  - Asymptomatic solitary bladder plasmocytoma: A case report and literature review.
PG  - e9347
LID - 10.1097/MD.0000000000009347 [doi]
AB  - RATIONALE: Solitary extramedullary plasmocytoma may arise in any organ, either as
      a primary tumor or as part of a systemic myeloma; if it rarely affects bladder,
      it presents with urinary symptoms. We describe the first case of asymptomatic BP 
      occasionally diagnosed in a patient with ascites. PATIENT CONCERNS: A 74-year-old
      woman with hepatitis C virus (HCV)-related liver cirrhosis presented with ascites
      and no urinary or other symptoms. DIAGNOSES: Routine blood tests were within
      normal ranges, except for mild elevation of transaminases due to chronic
      hepatitis. Abdominal ultrasound and computed tomography (CT) scanning showed
      multiple liver nodules suspected for carcinomas and, incidentally, a 18 mm solid 
      lesion of right bladder wall. OUTCOMES: She underwent transurethral resection of 
      the bladder tumor and percutaneous liver biopsies; final diagnosis was solitary
      bladder plasmocytoma (BP) and hepatocellular carcinoma (HCC), respectively. She
      was given chemoembolization of the main HCC nodule but no adjuvant treatment for 
      BP. At 3-month follow-up, total-body CT showed no signs of bladder disease nor
      distant metastases; unfortunately, she died one month later due to liver failure.
      LESSONS: This is the first reported case of asymptomatic BP. This rare neoplasm
      may pose difficulties in differential diagnosis with both bladder metastases and 
      the plasmocytoid variant of bladder transitional cell carcinoma. We also
      highlighted lack of factors predicting disease outcome as well as response to
      potential adjuvant treatments.
CI  - Copyright (c) 2017 The Authors. Published by Wolters Kluwer Health, Inc. All
      rights reserved.
FAU - Cormio, Luigi
AU  - Cormio L
AD  - Department of Urology and Renal Transplantation.
FAU - Mancini, Vito
AU  - Mancini V
AD  - Department of Urology and Renal Transplantation.
FAU - Calo, Beppe
AU  - Calo B
AD  - Department of Urology and Renal Transplantation.
FAU - Selvaggio, Oscar
AU  - Selvaggio O
AD  - Department of Urology and Renal Transplantation.
FAU - Mazzilli, Teobaldo
AU  - Mazzilli T
AD  - Department of Urology and Renal Transplantation.
FAU - Sanguedolce, Francesca
AU  - Sanguedolce F
AD  - Department of Pathology, University of Foggia, Foggia, Italy.
FAU - Carrieri, Giuseppe
AU  - Carrieri G
AD  - Department of Urology and Renal Transplantation.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - AIM
SB  - IM
MH  - Aged
MH  - Fatal Outcome
MH  - Female
MH  - Hepatitis C/complications
MH  - Humans
MH  - Incidental Findings
MH  - Liver Cirrhosis/virology
MH  - Plasmacytoma/*diagnostic imaging/*surgery
MH  - Urinary Bladder Neoplasms/*diagnostic imaging/*surgery
EDAT- 2018/02/03 06:00
MHDA- 2018/02/13 06:00
CRDT- 2018/02/03 06:00
PHST- 2018/02/03 06:00 [entrez]
PHST- 2018/02/03 06:00 [pubmed]
PHST- 2018/02/13 06:00 [medline]
AID - 10.1097/MD.0000000000009347 [doi]
AID - 00005792-201712150-00158 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2017 Dec;96(50):e9347. doi: 10.1097/MD.0000000000009347.