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Combined treatment of botulinumtoxin and robot-assisted rehabilitation therapy on poststroke, upper limb spasticity: A case report.

Abstract Spasticity is a major complication after stroke, and botulinumtoxin A (BoNT-A) injection is commonly used to manage focal spasticity. However, it is uncertain whether BoNT-A can improve voluntary motor control or activities of daily living function of paretic upper limbs. This study investigated whether BoNT-A injection combined with robot-assisted upper limb therapy improves voluntary motor control or functions of upper limbs after stroke.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title medicine
Publication Year Start




PMID- 29390585
OWN - NLM
STAT- MEDLINE
DCOM- 20180212
LR  - 20180212
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 96
IP  - 51
DP  - 2017 Dec
TI  - Combined treatment of botulinumtoxin and robot-assisted rehabilitation therapy on
      poststroke, upper limb spasticity: A case report.
PG  - e9468
LID - 10.1097/MD.0000000000009468 [doi]
AB  - RATIONALE: Spasticity is a major complication after stroke, and botulinumtoxin A 
      (BoNT-A) injection is commonly used to manage focal spasticity. However, it is
      uncertain whether BoNT-A can improve voluntary motor control or activities of
      daily living function of paretic upper limbs. This study investigated whether
      BoNT-A injection combined with robot-assisted upper limb therapy improves
      voluntary motor control or functions of upper limbs after stroke. PATIENT
      CONCERNS: Two subacute stroke patients were transferred to the Department of
      Rehabilitation. DIAGNOSES: Patients demonstrated spasticity in the upper
      extremity on the affected side. INTERVENTIONS: BoNT-A was injected into the
      paretic muscles of the shoulder, arm, and forearm of the 2 patients at the
      subacute stage. Conventional rehabilitation therapy and robot-assisted upper limb
      training were performed during the rehabilitation period. OUTCOMES: Manual
      dexterity, grip strength, muscle tone, and activities of daily living function
      were improved after multidisciplinary rehabilitation treatment. LESSONS: BoNT-A
      injection in combination with multidisciplinary rehabilitation treatment,
      including robot-assisted arm training, should be recommended for subacute spastic
      stroke patients to enhance appropriate motor recovery.
CI  - Copyright (c) 2017 The Authors. Published by Wolters Kluwer Health, Inc. All
      rights reserved.
FAU - Lee, So Young
AU  - Lee SY
AD  - Department of Rehabilitation Medicine, Jeju National University Hospital, Jeju
      National University School of Medicine, Jeju, Republic of Korea.
FAU - Jeon, Young Tae
AU  - Jeon YT
FAU - Kim, Bo Ryun
AU  - Kim BR
FAU - Han, Eun Young
AU  - Han EY
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - EC 3.4.24.69 (Botulinum Toxins)
SB  - AIM
SB  - IM
MH  - Adult
MH  - Arm
MH  - Botulinum Toxins/*therapeutic use
MH  - Combined Modality Therapy
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Muscle Spasticity/*etiology/rehabilitation
MH  - Robotics/*methods
MH  - Stroke/*complications
MH  - Stroke Rehabilitation/*methods
PMC - PMC5758287
EDAT- 2018/02/03 06:00
MHDA- 2018/02/13 06:00
CRDT- 2018/02/03 06:00
PHST- 2018/02/03 06:00 [entrez]
PHST- 2018/02/03 06:00 [pubmed]
PHST- 2018/02/13 06:00 [medline]
AID - 10.1097/MD.0000000000009468 [doi]
AID - 00005792-201712220-00172 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2017 Dec;96(51):e9468. doi: 10.1097/MD.0000000000009468.