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Testicular Cancer: Epidemiology, Diagnosis, and Management.

Abstract There were an estimated 8720 new cases of testicular cancer (TC) in the United States in 2016. The cause of the disease is complex, with several environmental and genetic risk factors. Although rare, the incidence has been steadily increasing. Fortunately, substantial advances in treatment have occurred over the last few decades, making TC one of the most curable malignancies. However, because TC typically occurs in younger men, considerations of the treatment impact on fertility, quality of life, and long-term toxicity are paramount; an individualized approach must be taken with patients based on their clinical and pathologic findings.
PMID
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Authors

Mayor MeshTerms
Keywords

Chemotherapy

Germ cell tumors

Nonseminoma

Orchiectomy

Radiation therapy

Retroperitoneal lymph node dissection

Seminoma

Testicular cancer

Journal Title the medical clinics of north america
Publication Year Start




PMID- 29406056
OWN - NLM
STAT- MEDLINE
DCOM- 20180208
LR  - 20180208
IS  - 1557-9859 (Electronic)
IS  - 0025-7125 (Linking)
VI  - 102
IP  - 2
DP  - 2018 Mar
TI  - Testicular Cancer: Epidemiology, Diagnosis, and Management.
PG  - 251-264
LID - S0025-7125(17)30157-8 [pii]
LID - 10.1016/j.mcna.2017.10.003 [doi]
AB  - There were an estimated 8720 new cases of testicular cancer (TC) in the United
      States in 2016. The cause of the disease is complex, with several environmental
      and genetic risk factors. Although rare, the incidence has been steadily
      increasing. Fortunately, substantial advances in treatment have occurred over the
      last few decades, making TC one of the most curable malignancies. However,
      because TC typically occurs in younger men, considerations of the treatment
      impact on fertility, quality of life, and long-term toxicity are paramount; an
      individualized approach must be taken with patients based on their clinical and
      pathologic findings.
CI  - Copyright (c) 2017 Elsevier Inc. All rights reserved.
FAU - Smith, Zachary L
AU  - Smith ZL
AD  - Section of Urology, Department of Surgery, The University of Chicago Medicine,
      5841 South Maryland Avenue, MC 6038, Chicago, IL 60637, USA. Electronic address: 
      [email protected]
FAU - Werntz, Ryan P
AU  - Werntz RP
AD  - Section of Urology, Department of Surgery, The University of Chicago Medicine,
      5841 South Maryland Avenue, MC 6038, Chicago, IL 60637, USA.
FAU - Eggener, Scott E
AU  - Eggener SE
AD  - Section of Urology, Department of Surgery, The University of Chicago Medicine,
      5841 South Maryland Avenue, MC 6038, Chicago, IL 60637, USA.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20171221
PL  - United States
TA  - Med Clin North Am
JT  - The Medical clinics of North America
JID - 2985236R
SB  - AIM
SB  - IM
MH  - Humans
MH  - Male
MH  - Testicular Neoplasms/*diagnosis/epidemiology/mortality/*therapy
OTO - NOTNLM
OT  - Chemotherapy
OT  - Germ cell tumors
OT  - Nonseminoma
OT  - Orchiectomy
OT  - Radiation therapy
OT  - Retroperitoneal lymph node dissection
OT  - Seminoma
OT  - Testicular cancer
EDAT- 2018/02/07 06:00
MHDA- 2018/02/09 06:00
CRDT- 2018/02/07 06:00
PHST- 2018/02/07 06:00 [entrez]
PHST- 2018/02/07 06:00 [pubmed]
PHST- 2018/02/09 06:00 [medline]
AID - S0025-7125(17)30157-8 [pii]
AID - 10.1016/j.mcna.2017.10.003 [doi]
PST - ppublish
SO  - Med Clin North Am. 2018 Mar;102(2):251-264. doi: 10.1016/j.mcna.2017.10.003. Epub
      2017 Dec 21.