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Ghost cell odontogenic carcinoma with suspected cholesterol granuloma of the maxillary sinus in a patient treated with combined modality therapy: A case report and the review of literature.

Abstract Ghost cell odontogenic carcinoma (GCOC) is a rare malignant odontogenic tumor with aggressive growth characteristics.
PMID
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Authors

Mayor MeshTerms

Cholesterol

Keywords
Journal Title medicine
Publication Year Start




PMID- 29443742
OWN - NLM
STAT- MEDLINE
DCOM- 20180222
LR  - 20180222
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 97
IP  - 7
DP  - 2018 Feb
TI  - Ghost cell odontogenic carcinoma with suspected cholesterol granuloma of the
      maxillary sinus in a patient treated with combined modality therapy: A case
      report and the review of literature.
PG  - e9816
LID - 10.1097/MD.0000000000009816 [doi]
AB  - RATIONALE: Ghost cell odontogenic carcinoma (GCOC) is a rare malignant
      odontogenic tumor with aggressive growth characteristics. PATIENT CONCERNS: A
      41-year-old Chinese male visited our hospital in 2013, with a 4-month history of 
      bloody purulent rhinorrhea with a peculiar smell in the right nasal cavity.
      DIAGNOSES: The patient suffered from recurrent GCOC with suspected cholesterol
      granuloma of the maxillary sinus. The patient was incorrectly diagnosed with a
      calcifying epithelial odontogenic tumor at his first recurrence. Physical
      examination, radiological examination, and histopathology were used to identify
      GCOC. INTERVENTIONS: Considering the recurrence of GCOC and poor effects of
      single surgery, postoperative adjuvant chemotherapy and concurrent
      chemoradiotherapy were performed after radical surgical excision. OUTCOMES: So
      far, no significant evidence has suggested recurrence or metastasis after a
      long-term follow-up. LESSONS: We advocate wide surgery with clean margins at the 
      first accurate diagnosis. Combined modality therapy could be taken for the
      recurrent GCOC. We expect to provide a new treatment strategy to prevent the
      growth of this neoplasm.
FAU - Qin, You
AU  - Qin Y
AD  - Cancer Center.
FAU - Lu, Yanwei
AU  - Lu Y
AD  - Cancer Center.
FAU - Zheng, Liduan
AU  - Zheng L
AD  - Department of Pathology.
FAU - Liu, Hong
AU  - Liu H
AD  - Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong
      University of Science and Technology, Wuhan, China.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 97C5T2UQ7J (Cholesterol)
SB  - AIM
SB  - IM
MH  - Adult
MH  - Carcinoma/complications/pathology/*therapy
MH  - Chemoradiotherapy
MH  - Chemotherapy, Adjuvant
MH  - *Cholesterol
MH  - Combined Modality Therapy/methods
MH  - Diagnostic Errors
MH  - Granuloma, Foreign-Body/etiology/pathology/*therapy
MH  - Humans
MH  - Male
MH  - Maxillary Sinus/pathology/surgery
MH  - Neoplasm Recurrence, Local/complications/pathology/*therapy
MH  - Odontogenic Tumors/complications/pathology/*therapy
MH  - Paranasal Sinus Diseases/etiology/pathology/*therapy
EDAT- 2018/02/15 06:00
MHDA- 2018/02/23 06:00
CRDT- 2018/02/15 06:00
PHST- 2018/02/15 06:00 [entrez]
PHST- 2018/02/15 06:00 [pubmed]
PHST- 2018/02/23 06:00 [medline]
AID - 10.1097/MD.0000000000009816 [doi]
AID - 00005792-201802160-00016 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2018 Feb;97(7):e9816. doi: 10.1097/MD.0000000000009816.