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Efficacy, safety, and mechanisms of herbal medicines used in the treatment of obesity: A protocol for systematic review.

Abstract This systematic review protocol aims to perform a protocol for assessing the effectiveness, safety, and mechanism of herbal medicines for the treatment of obesity and metabolic syndrome. Some systematic reviews conducted earlier have evaluated the efficacy of herbal medicine to treat obesity and metabolic syndrome. Owing to the huge burden imposed by obesity in the recent years, a need is felt for conducting new systematic reviews on the topic of obesity with a focus on randomized clinical trials, we felt the need.
PMID
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A systematic review of the efficacy and safety of herbal medicines used in the treatment of obesity.

Authors

Mayor MeshTerms

Phytotherapy

Keywords
Journal Title medicine
Publication Year Start




PMID- 29505506
OWN - NLM
STAT- MEDLINE
DCOM- 20180309
LR  - 20180309
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 97
IP  - 1
DP  - 2018 Jan
TI  - Efficacy, safety, and mechanisms of herbal medicines used in the treatment of
      obesity: A protocol for systematic review.
PG  - e8825
LID - 10.1097/MD.0000000000008825 [doi]
AB  - INTRODUCTION: This systematic review protocol aims to perform a protocol for
      assessing the effectiveness, safety, and mechanism of herbal medicines for the
      treatment of obesity and metabolic syndrome. Some systematic reviews conducted
      earlier have evaluated the efficacy of herbal medicine to treat obesity and
      metabolic syndrome. Owing to the huge burden imposed by obesity in the recent
      years, a need is felt for conducting new systematic reviews on the topic of
      obesity with a focus on randomized clinical trials, we felt the need. METHODS AND
      ANALYSIS: All relevant clinical trials that examine the effectiveness of herbal
      medicines for the treatment of obesity and metabolic syndrome without
      restrictions on publication status will be applied.Four electronic databases will
      be searched: PubMed, Scopus, Web of Science, and the Cochrane Central Register of
      Controlled Trials. The main outcome is expected to be an improvement in the body 
      weight, body mass index, waist circumference, waist-to-hip ratio, body fat
      (weight or mass of visceral adipose tissue, fat mass or percent), and
      appetite.Selection studies, data extraction, and risk of bias will be assessed
      independently by 2 authors. ETHICS AND DISSEMINATION: In this study, ethical
      approval is not required because the data that will be used are not subjects and 
      the results will be discussed through peer-reviewed publications. TRIAL
      REGISTRATION NUMBER: PROSPEROCRD42016049753.
CI  - Copyright (c) 2017 The Authors. Published by Wolters Kluwer Health, Inc. All
      rights reserved.
FAU - Payab, Moloud
AU  - Payab M
AD  - Obesity and Eating Habits Research Center, Endocrinology and Metabolism Molecular
      -Cellular Sciences Institute.
FAU - Hasani-Ranjbar, Shirin
AU  - Hasani-Ranjbar S
AD  - Obesity and Eating Habits Research Center, Endocrinology and Metabolism Molecular
      -Cellular Sciences Institute.
AD  - Endocrinology and Metabolism Research Center, Endocrinology and Metabolism
      Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran.
FAU - Aletaha, Azadeh
AU  - Aletaha A
AD  - Endocrinology and Metabolism Research Center, Endocrinology and Metabolism
      Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran.
FAU - Ghasemi, Nasrin
AU  - Ghasemi N
AD  - Endocrinology and Metabolism Research Center, Endocrinology and Metabolism
      Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran.
FAU - Qorbani, Mostafa
AU  - Qorbani M
AD  - Department of Community Medicine, Alborz University of Medical Sciences, Karaj,
      Iran.
AD  - Chronic Diseases Research Center, Endocrinology and Metabolism Population
      Sciences Institute.
FAU - Atlasi, Rasha
AU  - Atlasi R
AD  - Evidence Based Practice Research Center, Endocrinology and Metabolism Clinical
      Sciences Institute.
FAU - Abdollahi, Mohammad
AU  - Abdollahi M
AD  - Department of Toxicology and Pharmacology, Faculty of Pharmacy, and
      Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences,
      Tehran, Iran.
FAU - Larijani, Bagher
AU  - Larijani B
AD  - Endocrinology and Metabolism Research Center, Endocrinology and Metabolism
      Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 0 (Plant Extracts)
SB  - AIM
SB  - IM
MH  - Humans
MH  - Obesity/*drug therapy
MH  - *Phytotherapy
MH  - Plant Extracts/*therapeutic use
EDAT- 2018/03/06 06:00
MHDA- 2018/03/10 06:00
CRDT- 2018/03/06 06:00
PHST- 2018/03/06 06:00 [entrez]
PHST- 2018/03/06 06:00 [pubmed]
PHST- 2018/03/10 06:00 [medline]
AID - 10.1097/MD.0000000000008825 [doi]
AID - 00005792-201801050-00003 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2018 Jan;97(1):e8825. doi: 10.1097/MD.0000000000008825.