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Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer.

Abstract This study aimed to explore the efficacy and toxicity of image-guided stereotactic body radiotherapy (IGSBR) by helical tomotherapy in patients with lung cancer among Chinese Han population.A total of 21 patients with stage I lung cancer were included. They received a total of 60 Gy factions IGSBR. The outcomes included complete response (CR), partial response (PR), stable disease (SD), progress disease (PD), overall response rate (ORR), and overall survival (OS). In addition, toxicities were also recorded in this study.Three-year CR, PR, SD, PD, ORR, and OS were 47.6%, 38.1%, 9.5%, 4.8%, 85.7%, and 48.0 months, respectively. Additionally, mild toxicities were found in this study.This study demonstrated that IGSBR is efficacious for patients with stage I lung cancer with mild toxicities among Chinese Han population.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title medicine
Publication Year Start




PMID- 29505510
OWN - NLM
STAT- MEDLINE
DCOM- 20180309
LR  - 20180309
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 97
IP  - 1
DP  - 2018 Jan
TI  - Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in
      patients with lung cancer.
PG  - e9243
LID - 10.1097/MD.0000000000009243 [doi]
AB  - This study aimed to explore the efficacy and toxicity of image-guided
      stereotactic body radiotherapy (IGSBR) by helical tomotherapy in patients with
      lung cancer among Chinese Han population.A total of 21 patients with stage I lung
      cancer were included. They received a total of 60 Gy factions IGSBR. The outcomes
      included complete response (CR), partial response (PR), stable disease (SD),
      progress disease (PD), overall response rate (ORR), and overall survival (OS). In
      addition, toxicities were also recorded in this study.Three-year CR, PR, SD, PD, 
      ORR, and OS were 47.6%, 38.1%, 9.5%, 4.8%, 85.7%, and 48.0 months, respectively. 
      Additionally, mild toxicities were found in this study.This study demonstrated
      that IGSBR is efficacious for patients with stage I lung cancer with mild
      toxicities among Chinese Han population.
CI  - Copyright (c) 2017 The Authors. Published by Wolters Kluwer Health, Inc. All
      rights reserved.
FAU - Chen, Xiang-Ru
AU  - Chen XR
AD  - Department of Ultrasound, The Second Affiliated Hospital of Mudanjiang Medical
      University.
FAU - Dong, Jia-Nan
AU  - Dong JN
AD  - Department of Rehabilitation Comprehensive Laboratory.
FAU - Zhang, Fan
AU  - Zhang F
AD  - School of Image, Mudanjiang Medical University.
FAU - Yao, Tian-Ling
AU  - Yao TL
AD  - School of Image, Mudanjiang Medical University.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - AIM
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Asian Continental Ancestry Group
MH  - Carcinoma/*radiotherapy
MH  - Carcinoma, Non-Small-Cell Lung/radiotherapy
MH  - Female
MH  - Humans
MH  - Lung Neoplasms/*radiotherapy
MH  - Male
MH  - Middle Aged
MH  - Radiotherapy, Image-Guided
MH  - Radiotherapy, Intensity-Modulated
MH  - Retrospective Studies
EDAT- 2018/03/06 06:00
MHDA- 2018/03/10 06:00
CRDT- 2018/03/06 06:00
PHST- 2018/03/06 06:00 [entrez]
PHST- 2018/03/06 06:00 [pubmed]
PHST- 2018/03/10 06:00 [medline]
AID - 10.1097/MD.0000000000009243 [doi]
AID - 00005792-201801050-00007 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2018 Jan;97(1):e9243. doi: 10.1097/MD.0000000000009243.