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A demonstration area for type 2 diabetes prevention in Barranquilla and Juan Mina (Colombia): Baseline characteristics of the study participants.

Abstract Type 2 diabetes (T2D) imposes a heavy public health burden in both developed and developing countries. It is necessary to understand the effect of T2D in different settings and population groups. This report aimed to present baseline characteristics of study participants in the demonstration area for the "Type 2 Diabetes Prevention in Barranquilla and Juan Mina" (DEMOJUAN) project after randomization and to compare their fasting and 2-hour glucose levels according to lifestyle and T2D risk factor levels.The DEMOJUAN project is a randomized controlled field trial. Study participants were recruited from study sites using population-wide screening using the Finnish Diabetes Risk Score (FINDRISC) questionnaire. All volunteers with FINDRISC of ≥13 points were invited to undergo an oral glucose tolerance test (OGTT). Participant inclusion criteria for the upcoming field trial were either FINDRISC of ≥13 points and 2-hour post-challenge glucose level of 7.0 to 11.0 mmol/L or FINDRISC of ≥13 points and fasting plasma glucose level of 6.1 to 6.9 mmol/L. Lifestyle habits and risk factors for T2D were assessed by trained interviewers using a validated questionnaire.Among the 14,193 participants who completed the FINDRISC questionnaire, 35% (n = 4915) had a FINDRISC score of ≥13 points and 47% (n = 2306) agreed to undergo the OGTT. Approximately, 33% (n = 772) of participants underwent the OGTT and met the entry criteria; these participants were randomized into 3 groups. There were no statistically significant differences found in anthropometric or lifestyle risk factors, distribution of the glucose metabolism categories, or other diabetes risk factors between the 3 groups (P > .05). Women with a past history of hyperglycaemia had significantly higher fasting glucose levels than those without previous hyperglycaemia (103 vs 99 mg/dL; P < .05).Lifestyle habits and risk factors were evenly distributed among the 3 study groups. No differences were found in fasting or 2-hour glucose levels among different lifestyle or risk factor categories with the exception of body mass index, past history of hyperglycaemia, and age of ≥64 years in women.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title medicine
Publication Year Start




PMID- 29505512
OWN - NLM
STAT- MEDLINE
DCOM- 20180309
LR  - 20180309
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 97
IP  - 1
DP  - 2018 Jan
TI  - A demonstration area for type 2 diabetes prevention in Barranquilla and Juan Mina
      (Colombia): Baseline characteristics of the study participants.
PG  - e9285
LID - 10.1097/MD.0000000000009285 [doi]
AB  - Type 2 diabetes (T2D) imposes a heavy public health burden in both developed and 
      developing countries. It is necessary to understand the effect of T2D in
      different settings and population groups. This report aimed to present baseline
      characteristics of study participants in the demonstration area for the "Type 2
      Diabetes Prevention in Barranquilla and Juan Mina" (DEMOJUAN) project after
      randomization and to compare their fasting and 2-hour glucose levels according to
      lifestyle and T2D risk factor levels.The DEMOJUAN project is a randomized
      controlled field trial. Study participants were recruited from study sites using 
      population-wide screening using the Finnish Diabetes Risk Score (FINDRISC)
      questionnaire. All volunteers with FINDRISC of &gt;/=13 points were invited to
      undergo an oral glucose tolerance test (OGTT). Participant inclusion criteria for
      the upcoming field trial were either FINDRISC of &gt;/=13 points and 2-hour
      post-challenge glucose level of 7.0 to 11.0 mmol/L or FINDRISC of &gt;/=13 points
      and fasting plasma glucose level of 6.1 to 6.9 mmol/L. Lifestyle habits and risk 
      factors for T2D were assessed by trained interviewers using a validated
      questionnaire.Among the 14,193 participants who completed the FINDRISC
      questionnaire, 35% (n = 4915) had a FINDRISC score of &gt;/=13 points and 47% (n =
      2306) agreed to undergo the OGTT. Approximately, 33% (n = 772) of participants
      underwent the OGTT and met the entry criteria; these participants were randomized
      into 3 groups. There were no statistically significant differences found in
      anthropometric or lifestyle risk factors, distribution of the glucose metabolism 
      categories, or other diabetes risk factors between the 3 groups (P &gt; .05). Women 
      with a past history of hyperglycaemia had significantly higher fasting glucose
      levels than those without previous hyperglycaemia (103 vs 99 mg/dL; P &lt;
      .05).Lifestyle habits and risk factors were evenly distributed among the 3 study 
      groups. No differences were found in fasting or 2-hour glucose levels among
      different lifestyle or risk factor categories with the exception of body mass
      index, past history of hyperglycaemia, and age of &gt;/=64 years in women. TRIAL
      REGISTRATION: NCT01296100 (2/12/2011; Clinical trials.gov).
CI  - Copyright (c) 2017 The Authors. Published by Wolters Kluwer Health, Inc. All
      rights reserved.
FAU - Acosta, Tania
AU  - Acosta T
AD  - Department of Public Health, Universidad del Norte, Barranquilla, Colombia.
FAU - Barengo, Noel C
AU  - Barengo NC
AD  - Department of Medical and Population Health Research, Herbert Wertheim College of
      Medicine, Florida International University, Miami, Florida.
FAU - Arrieta, Astrid
AU  - Arrieta A
AD  - Centro de Investigation Sanitaria, Barranquilla, Colombia.
FAU - Ricaurte, Carlos
AU  - Ricaurte C
AD  - Centro de Investigation Sanitaria, Barranquilla, Colombia.
FAU - Tuomilehto, Jaakko O
AU  - Tuomilehto JO
AD  - Dasman Diabetes Institute, Dasman, Kuwait.
AD  - Department of Neuroscience and Preventive Medicine, Danube-University Krems,
      Krems, Austria.
AD  - Disease Risk Unit, National Institute for Health and Welfare.
AD  - Department of Public Health, University of Helsinki, Helsinki, Finland.
AD  - Saudi Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia.
LA  - eng
SI  - ClinicalTrials.gov/NCT01296100
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 0 (Blood Glucose)
SB  - AIM
SB  - IM
MH  - Adult
MH  - Aged
MH  - Blood Glucose
MH  - Colombia
MH  - Diabetes Mellitus, Type 2/*prevention &amp; control
MH  - Female
MH  - Humans
MH  - Life Style
MH  - Male
MH  - Middle Aged
MH  - Risk Factors
EDAT- 2018/03/06 06:00
MHDA- 2018/03/10 06:00
CRDT- 2018/03/06 06:00
PHST- 2018/03/06 06:00 [entrez]
PHST- 2018/03/06 06:00 [pubmed]
PHST- 2018/03/10 06:00 [medline]
AID - 10.1097/MD.0000000000009285 [doi]
AID - 00005792-201801050-00009 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2018 Jan;97(1):e9285. doi: 10.1097/MD.0000000000009285.