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Ankylosing spondylitis associated with Still's disease: should it be considered a pathophysiologic link or a simple association?

Abstract Ankylosing spondylitis is a chronic inflammatory rheumatism; it is part of the group of spondyloarthrites. General signs such as fever and weight loss are of little importance. Adult Still's disease is a rare systemic condition, a diagnosis of exclusion commonly characterized by high hectic fever, rash, arthritis and various systemic manifestations. Few cases of ankylosing spondylitis associated with adult Still's disease have been described in the literature. We here report the case of a 31-year old patient followed up for ankylosing spondylitis presenting with fever which had lasted for a long time and clinico-biological signs compatible with adult Still's disease. A possible pathophysiologic link between the two diseases may be suggested, even if their simultaneous occurrence has been rarely reported in the literature.
PMID
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Authors

Mayor MeshTerms
Keywords

Ankylosing spondylitis

Still

fever

glucocorticoids

Journal Title the pan african medical journal
Publication Year Start




PMID- 29515750
OWN - NLM
STAT- MEDLINE
DCOM- 20180313
LR  - 20180313
IS  - 1937-8688 (Electronic)
VI  - 28
DP  - 2017
TI  - [Ankylosing spondylitis associated with Still's disease: should it be considered 
      a pathophysiologic link or a simple association?]
PG  - 132
LID - 10.11604/pamj.2017.28.132.5607 [doi]
AB  - Ankylosing spondylitis is a chronic inflammatory rheumatism; it is part of the
      group of spondyloarthrites. General signs such as fever and weight loss are of
      little importance. Adult Still's disease is a rare systemic condition, a
      diagnosis of exclusion commonly characterized by high hectic fever, rash,
      arthritis and various systemic manifestations. Few cases of ankylosing
      spondylitis associated with adult Still's disease have been described in the
      literature. We here report the case of a 31-year old patient followed up for
      ankylosing spondylitis presenting with fever which had lasted for a long time and
      clinico-biological signs compatible with adult Still's disease. A possible
      pathophysiologic link between the two diseases may be suggested, even if their
      simultaneous occurrence has been rarely reported in the literature.
FAU - Aradoini, Nassira
AU  - Aradoini N
AD  - Faculte de Medecine, Universite Sidi Mohamed Ben Abdallah, Service de
      Rhumatologie, Centre Hospitalier Universitaire Hassan II, Fes, Maroc.
FAU - Talbi, Sofia
AU  - Talbi S
AD  - Faculte de Medecine, Universite Sidi Mohamed Ben Abdallah, Service de
      Rhumatologie, Centre Hospitalier Universitaire Hassan II, Fes, Maroc.
FAU - Azzouzi, Hamida
AU  - Azzouzi H
AD  - Faculte de Medecine, Universite Sidi Mohamed Ben Abdallah, Service de
      Rhumatologie, Centre Hospitalier Universitaire Hassan II, Fes, Maroc.
FAU - Abourazzak, Fatima Zahra
AU  - Abourazzak FZ
AD  - Faculte de Medecine, Universite Sidi Mohamed Ben Abdallah, Service de
      Rhumatologie, Centre Hospitalier Universitaire Hassan II, Fes, Maroc.
FAU - Khibri, Hajar
AU  - Khibri H
AD  - Service de Medecine Interne, Centre Hospitalier Universitaire Hassan II, Fes,
      Maroc.
FAU - Berrady, Rhizlane
AU  - Berrady R
AD  - Service de Medecine Interne, Centre Hospitalier Universitaire Hassan II, Fes,
      Maroc.
FAU - Bono, Wafaa
AU  - Bono W
AD  - Service de Medecine Interne, Centre Hospitalier Universitaire Hassan II, Fes,
      Maroc.
FAU - Harzy, Taoufik
AU  - Harzy T
AD  - Faculte de Medecine, Universite Sidi Mohamed Ben Abdallah, Service de
      Rhumatologie, Centre Hospitalier Universitaire Hassan II, Fes, Maroc.
LA  - fre
PT  - Case Reports
PT  - Journal Article
TT  - Spondylarthrite ankylosante et maladie de Still: un lien physiopathologique ou
      une simple association?
DEP - 20171010
PL  - Uganda
TA  - Pan Afr Med J
JT  - The Pan African medical journal
JID - 101517926
SB  - IM
MH  - Adult
MH  - Fever/*etiology
MH  - Humans
MH  - Male
MH  - Spondylitis, Ankylosing/*etiology/physiopathology
MH  - Still's Disease, Adult-Onset/*complications/diagnosis/physiopathology
PMC - PMC5837172
OTO - NOTNLM
OT  - Ankylosing spondylitis
OT  - Still
OT  - fever
OT  - glucocorticoids
EDAT- 2018/03/09 06:00
MHDA- 2018/03/14 06:00
CRDT- 2018/03/09 06:00
PHST- 2014/10/13 00:00 [received]
PHST- 2015/01/13 00:00 [accepted]
PHST- 2018/03/09 06:00 [entrez]
PHST- 2018/03/09 06:00 [pubmed]
PHST- 2018/03/14 06:00 [medline]
AID - 10.11604/pamj.2017.28.132.5607 [doi]
AID - PAMJ-28-132 [pii]
PST - epublish
SO  - Pan Afr Med J. 2017 Oct 10;28:132. doi: 10.11604/pamj.2017.28.132.5607.
      eCollection 2017.