Onset of HLA-B27-associated diseases in diabetic patient during a period of religious fasting: A case report. |
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Abstract | The association between human leukocyte antigen B27 (HLA-B27) with its associated diseases is far from complete. The role of HLA-B27 in disease susceptibility is still not known, although many suggestions have been proposed. |
PMID | 29538202 |
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A familial study of the inheritance of HLA-B27-positive acute anterior uveitis. Outcomes of HLA-B27-positive and HLA-B27-negative acute anterior uveitis. Efficacy of golimumab on recurrent uveitis in HLA-B27-positive ankylosing spondylitis. Acute anterior uveitis, ankylosing spondylitis, back pain, and HLA-B27. |
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Mayor MeshTerms | |
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Journal Title | medicine |
Publication Year Start | 2018-01-01 |
PMID- 29538202 OWN - NLM STAT- MEDLINE DCOM- 20180321 LR - 20180321 IS - 1536-5964 (Electronic) IS - 0025-7974 (Linking) VI - 97 IP - 11 DP - 2018 Mar TI - Onset of HLA-B27-associated diseases in diabetic patient during a period of religious fasting: A case report. PG - e0104 LID - 10.1097/MD.0000000000010104 [doi] AB - RATIONALE: The association between human leukocyte antigen B27 (HLA-B27) with its associated diseases is far from complete. The role of HLA-B27 in disease susceptibility is still not known, although many suggestions have been proposed. PATIENT CONCERNS: The patient was a 46-year-old policeman with a history of obesity, diabetes, and hypertension. He was a Shaolin lay disciple who fasted at the Shaolin temple for at least 1 week each year since 2014. DIAGNOSES: The patient suffered three different HLA-B27-associated diseases including acute anterior uveitis, ulcerative colitis, and ankylosing spondylitis, from 2014 to 2016 because of prolonged fasting. INTERVENTIONS: The patient accept standard treatment after the diagnosis of acute anterior uveitis, ulcerative colitis, and ankylosing spondylitis. OUTCOMES: The patient's symptoms and signs of acute anterior uveitis, ulcerative colitis, and ankylosing spondylitis were all relieved within one week after the clinical treatment. LESSONS: Our case suggested that prolonged fasting may lead to the onset of HLA-B27-associated diseases in diabetic patient. FAU - Lin, Zhenyun AU - Lin Z AD - Department of Obstetrics and Gynecology, Hangzhou Maternity Hospital. FAU - Zhu, Binbin AU - Zhu B AD - Eye Center, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China. FAU - Jin, Xiuming AU - Jin X AD - Eye Center, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China. LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Medicine (Baltimore) JT - Medicine JID - 2985248R RN - 0 (Anti-Inflammatory Agents, Non-Steroidal) RN - 0 (HLA-B27 Antigen) RN - 0 (Ophthalmic Solutions) RN - 4Q81I59GXC (Mesalamine) SB - AIM SB - IM MH - Anti-Inflammatory Agents, Non-Steroidal/administration & dosage MH - *Colitis, Ulcerative/diagnosis/drug therapy/etiology MH - Diabetes Mellitus/diagnosis/physiopathology MH - Diagnostic Techniques, Ophthalmological MH - Fasting/*adverse effects MH - HLA-B27 Antigen/*analysis MH - Humans MH - Male MH - Mesalamine/*administration & dosage MH - Middle Aged MH - Ophthalmic Solutions/administration & dosage MH - Recurrence MH - *Spondylitis, Ankylosing/diagnosis/drug therapy/etiology MH - Treatment Outcome MH - *Uveitis, Anterior/diagnosis/drug therapy/etiology EDAT- 2018/03/15 06:00 MHDA- 2018/03/22 06:00 CRDT- 2018/03/15 06:00 PHST- 2018/03/15 06:00 [entrez] PHST- 2018/03/15 06:00 [pubmed] PHST- 2018/03/22 06:00 [medline] AID - 10.1097/MD.0000000000010104 [doi] AID - 00005792-201803160-00008 [pii] PST - ppublish SO - Medicine (Baltimore). 2018 Mar;97(11):e0104. doi: 10.1097/MD.0000000000010104.