PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

What is the superior surgical strategy for bi-level cervical spondylosis-anterior cervical disc replacement or anterior cervical decompression and fusion?: A meta-analysis from 11 studies.

Abstract Nowadays, anterior cervical artificial disc replacement (ACDR) has achieved favorable outcomes in treatment for patients with single-level cervical spondylosis. However, It is still controversial that whether or not it will become a potent therapeutic alternation in treating 2 contiguous levels cervical spondylosis compared with anterior cervical decompression and fusion (ACDF). Therefore, we conducted a systematic review and meta-analysis to compare the efficacy and safety of ACDR and ACDF in patients with 2 contiguous levels cervical spondylosis.
PMID
Related Publications

Efficacy and safety of Mobi-C cervical artificial disc versus anterior discectomy and fusion in patients with symptomatic degenerative disc disease: A meta-analysis.

Comparison of the short- and long-term treatment effect of cervical disk replacement and anterior cervical disk fusion: a meta-analysis.

Five-year clinical results of cervical total disc replacement compared with anterior discectomy and fusion for treatment of 2-level symptomatic degenerative disc disease: a prospective, randomized, controlled, multicenter investigational device exemption clinical trial.

Mid- to Long-Term Outcomes of Cervical Disc Arthroplasty versus Anterior Cervical Discectomy and Fusion for Treatment of Symptomatic Cervical Disc Disease: A Systematic Review and Meta-Analysis of Eight Prospective Randomized Controlled Trials.

Artificial discs for lumbar and cervical degenerative disc disease -update: an evidence-based analysis.

Authors

Mayor MeshTerms
Keywords
Journal Title medicine
Publication Year Start




PMID- 29595628
OWN - NLM
STAT- In-Process
LR  - 20180329
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 97
IP  - 13
DP  - 2018 Mar
TI  - What is the superior surgical strategy for bi-level cervical spondylosis-anterior
      cervical disc replacement or anterior cervical decompression and fusion?: A
      meta-analysis from 11 studies.
PG  - e0005
LID - 10.1097/MD.0000000000010005 [doi]
AB  - BACKGROUND: Nowadays, anterior cervical artificial disc replacement (ACDR) has
      achieved favorable outcomes in treatment for patients with single-level cervical 
      spondylosis. However, It is still controversial that whether or not it will
      become a potent therapeutic alternation in treating 2 contiguous levels cervical 
      spondylosis compared with anterior cervical decompression and fusion (ACDF).
      Therefore, we conducted a systematic review and meta-analysis to compare the
      efficacy and safety of ACDR and ACDF in patients with 2 contiguous levels
      cervical spondylosis. METHODS: According to the computer-based online search,
      PubMed, Embase, Web of Science, and Cochrane Library for articles published
      before July 1, 2017 were searched. The following outcome measures were extracted:
      neck disability index (NDI), visual analog scale (VAS) neck, VAS arm, Short Form 
      (SF)-12 mental component summary (MCS), SF-12 physical component summary (PCS),
      overall clinical success (OCS), patient satisfaction (PS), device-related adverse
      event (DRAE), subsequent surgical intervention (SSI), neurological deterioration 
      (ND), and adjacent segment degeneration (ASD). Methodological quality was
      evaluated independently by 2 reviewers using the Furlan for randomized controlled
      trial (RCT) and MINORS scale for clinical controlled trials (CCT). The
      chi-squared test and Higgin I test were used to evaluate the heterogeneity. A P <
      .10 for the chi-squared test or I values exceeding 50% indicated substantial
      heterogeneity and a random-effect model was applied; otherwise, a fixed-effect
      model was used. All quantitative data were analyzed by the Review Manager 5.2
      (The Nordic Cochrane Centre, The Cochrane Collaboration, Copenhagen, Denmark).
      RESULTS: Nine RCTs and 2 CCT studies containing 2715 patients were included for
      this meta-analysis. The pooled analysis indicated that the ACDR group is superior
      to ACDF in NDI, VAS neck, PCS score, OCS, PS, DRAE, ASD, and SSI. However, the
      pooled results indicate that there was no significant difference in the ND, VAS
      arm and in MCS score. CONCLUSIONS: The present meta-analysis suggests that for
      bi-level cervical spondylosis, ACDR appears to provide superior clinical
      effectiveness and safety effects than ACDF. In the future, more high-quality RCTs
      are warranted to enhance this conclusion.
FAU - Zhao, He
AU  - Zhao H
AD  - Department of Orthopedics III, Beijing University of Chinese Medicine, Dongzhimen
      Hospital, Beijing.
FAU - Duan, Li-Jun
AU  - Duan LJ
AD  - Department of Orthopedics, Bayannaoer City Hospital, Bayannaoer City.
FAU - Gao, Yu-Shan
AU  - Gao YS
AD  - School of Basic Medical Sciences, Beijing University of Chinese Medicine.
FAU - Yang, Yong-Dong
AU  - Yang YD
AD  - Department of Orthopedics III, Beijing University of Chinese Medicine, Dongzhimen
      Hospital, Beijing.
FAU - Tang, Xiang-Sheng
AU  - Tang XS
AD  - Department of Orthopedics, China-Japan Friendship Hospital Affiliated to Beijing 
      University of Chinese Medicine, Beijing, China.
FAU - Zhao, Ding-Yan
AU  - Zhao DY
AD  - Department of Orthopedics III, Beijing University of Chinese Medicine, Dongzhimen
      Hospital, Beijing.
FAU - Xiong, Yang
AU  - Xiong Y
AD  - Department of Orthopedics III, Beijing University of Chinese Medicine, Dongzhimen
      Hospital, Beijing.
FAU - Hu, Zhen-Guo
AU  - Hu ZG
AD  - Department of Orthopedics III, Beijing University of Chinese Medicine, Dongzhimen
      Hospital, Beijing.
FAU - Li, Chuan-Hong
AU  - Li CH
AD  - Department of Orthopedics III, Beijing University of Chinese Medicine, Dongzhimen
      Hospital, Beijing.
FAU - Yu, Xing
AU  - Yu X
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
EDAT- 2018/03/30 06:00
MHDA- 2018/03/30 06:00
CRDT- 2018/03/30 06:00
PHST- 2018/03/30 06:00 [entrez]
PHST- 2018/03/30 06:00 [pubmed]
PHST- 2018/03/30 06:00 [medline]
AID - 10.1097/MD.0000000000010005 [doi]
AID - 00005792-201803300-00001 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2018 Mar;97(13):e0005. doi: 10.1097/MD.0000000000010005.