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Intrathyroidal ectopic thymus in children: A benign lesion.

Abstract As ultrasound is commonly used these days, more and more lesions are found incidentally, including simple cysts, isoechoic nodules, and hypoechoic nodules, such as ectopic thymus. We here report the prevalence of ectopic thymus and its natural course.We retrospectively reviewed the charts of 690 subjects (342 males, 348 females) who were under 18 years old and had undergone neck or thyroid ultrasound at Hallym University Sacred Heart Hospital from January 2014 to June 2017. Ectopic thymus was defined when the incidental lesion was hypo- to iso-echoic compared to adjacent muscles with vascularity and did not have a connection to the thymus in the mediastinum.Of the 690 children, 16 (9 males, 7 females; median and ranges of age at diagnosis, 13 months and 18 days to 10 years) were diagnosed as having ectopic thymus. The most common location of ectopic thymus was in the inferior aspect of the left thyroid lobe. The median and ranges of the longest diameter at the time of initial diagnosis was 22.5 mm and 8 mm to 38 mm, respectively. Four cases underwent follow-up ultrasound, of which 3 cases showed no change in size and 1 case showed decreased size.Ectopic thymus should be kept in mind when a lesion is found in the neck and thyroid incidentally, and physicians should reassure parents about its benign course.
PMID
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Authors

Mayor MeshTerms

Thymus Gland

Keywords
Journal Title medicine
Publication Year Start




PMID- 29620644
OWN - NLM
STAT- MEDLINE
DCOM- 20180416
LR  - 20180416
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 97
IP  - 14
DP  - 2018 Apr
TI  - Intrathyroidal ectopic thymus in children: A benign lesion.
PG  - e0282
LID - 10.1097/MD.0000000000010282 [doi]
AB  - As ultrasound is commonly used these days, more and more lesions are found
      incidentally, including simple cysts, isoechoic nodules, and hypoechoic nodules, 
      such as ectopic thymus. We here report the prevalence of ectopic thymus and its
      natural course.We retrospectively reviewed the charts of 690 subjects (342 males,
      348 females) who were under 18 years old and had undergone neck or thyroid
      ultrasound at Hallym University Sacred Heart Hospital from January 2014 to June
      2017. Ectopic thymus was defined when the incidental lesion was hypo- to
      iso-echoic compared to adjacent muscles with vascularity and did not have a
      connection to the thymus in the mediastinum.Of the 690 children, 16 (9 males, 7
      females; median and ranges of age at diagnosis, 13 months and 18 days to 10
      years) were diagnosed as having ectopic thymus. The most common location of
      ectopic thymus was in the inferior aspect of the left thyroid lobe. The median
      and ranges of the longest diameter at the time of initial diagnosis was 22.5 mm
      and 8 mm to 38 mm, respectively. Four cases underwent follow-up ultrasound, of
      which 3 cases showed no change in size and 1 case showed decreased size.Ectopic
      thymus should be kept in mind when a lesion is found in the neck and thyroid
      incidentally, and physicians should reassure parents about its benign course.
FAU - Bang, Myung Hoon
AU  - Bang MH
AD  - Department of Pediatrics.
FAU - Shin, JinShik
AU  - Shin J
AD  - Department of Pediatrics.
FAU - Lee, Kwan Seop
AU  - Lee KS
AD  - Department of Radiology, Hallym University Sacred Heart Hospital, Hallym
      University College of Medicine, Anyang, Korea.
FAU - Kang, Min Jae
AU  - Kang MJ
AD  - Department of Pediatrics.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - AIM
SB  - IM
MH  - Child
MH  - Child, Preschool
MH  - Choristoma/diagnostic imaging/*epidemiology/pathology
MH  - Female
MH  - Humans
MH  - Incidental Findings
MH  - Infant
MH  - Male
MH  - Prevalence
MH  - Retrospective Studies
MH  - *Thymus Gland
MH  - Thyroid Diseases/diagnostic imaging/*epidemiology/pathology
MH  - Thyroid Gland/diagnostic imaging/pathology
MH  - Ultrasonography
EDAT- 2018/04/06 06:00
MHDA- 2018/04/17 06:00
CRDT- 2018/04/06 06:00
PHST- 2018/04/06 06:00 [entrez]
PHST- 2018/04/06 06:00 [pubmed]
PHST- 2018/04/17 06:00 [medline]
AID - 10.1097/MD.0000000000010282 [doi]
AID - 00005792-201804060-00022 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2018 Apr;97(14):e0282. doi: 10.1097/MD.0000000000010282.