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PMID- 29685130
DCOM- 20180430
LR  - 20180501
IS  - 1471-2415 (Electronic)
IS  - 1471-2415 (Linking)
VI  - 18
IP  - 1
DP  - 2018 Apr 23
TI  - Cataract surgery in patients with corneal opacities.
PG  - 106
LID - 10.1186/s12886-018-0765-7 [doi]
AB  - BACKGROUND: Investigating the efficacy and safety of phacoemulsification with
      intraocular lens (IOL) implantation in corneal opacities. METHODS: This
      retrospective study was conducted in a tertiary medical center. Twenty-three eyes
      of 19 patients with cataracts and corneal opacities obscuring the pupillary
      center having received phacoemulsification with IOL insertion without any
      ancillary techniques were enrolled. The primary study outcome measures were
      uncorrected and best corrected visual acuity (BCVA), and complications.
      Backscatters of corneal scar lesions were evaluated by slit lamp-based haze
      grading, Scheimpflug Pentacam and anterior segment optical coherence tomography
      (ASOCT). Visual outcomes after cataract surgeries and improvement range were used
      to determine the safety and efficacy of cataract surgery for our patients.
      RESULTS: All patients underwent uneventful capsulorhexis and phacoemulsification.
      The mean age was 72.22 +/- 10.1 years, and the mean follow-up period was 18.57
      +/- 15.42 months. The mean BCVA significantly improved from 1.45 +/- 0.65
      preoperatively to 0.94 +/- 0.55 logMAR postoperatively (p < 0.001), and the
      number of eyes with a BCVA of 20/100 or better increased from 4 to 14.
      Complications included corneal edema in two eyes and reactivation of the previous
      corneal pathology in five eyes. Four eyes did not achieve an improvement in
      visual acuity after surgery, which may have been due to co-existing ocular
      co-morbidities. Both Pentacam corneal densitometry and ASOCT demonstrated no
      significant correlations with final visual outcome. However, a statistically
      significant relationship between the severity of corneal opacity and improvement 
      range in BCVA (r = - 0.782, P = 0.001) was found by our OCT grading method.
      CONCLUSIONS: Phacoemulsification and IOL implantation in selected cases of
      coexisting cataracts and corneal opacities is safe that can provide suboptimal
      but long-term vision when penetrating keratoplasty is not possible or at
      high-risk of graft failure. ASOCT is a simple tool to predict visual outcomes
      after cataract surgery in opacified corneas.
FAU - Ho, Yi-Ju
AU  - Ho YJ
AD  - Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taiwan.
FAU - Sun, Chi-Chin
AU  - Sun CC
AD  - Department of Ophthalmology, Chang Gung Memorial Hospital, 6F, Mai-Jing Road,
      An-Leh District, Keelung, Taiwan, Republic of China. [email protected]
AD  - Department of Chinese Medicine, College of Medicine, Chang Gung University,
      Taoyuan, Taiwan. [email protected]
FAU - Chen, Hung-Chi
AU  - Chen HC
AD  - Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taiwan.
LA  - eng
PT  - Journal Article
DEP - 20180423
PL  - England
TA  - BMC Ophthalmol
JT  - BMC ophthalmology
JID - 100967802
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - *Cataract/complications
MH  - Corneal Opacity/complications/*surgery
MH  - Female
MH  - Humans
MH  - Lens Implantation, Intraocular/adverse effects/*methods
MH  - Male
MH  - Middle Aged
MH  - Phacoemulsification/adverse effects/*methods
MH  - Postoperative Complications/etiology
MH  - Refraction, Ocular
MH  - Retrospective Studies
MH  - Visual Acuity
PMC - PMC5913879
OT  - Anterior segment optical coherence tomography
OT  - Cataract
OT  - Corneal densitometry
OT  - Corneal opacities
OT  - Phacoemulsification
EDAT- 2018/04/25 06:00
MHDA- 2018/05/01 06:00
CRDT- 2018/04/25 06:00
PHST- 2017/09/17 00:00 [received]
PHST- 2018/04/03 00:00 [accepted]
PHST- 2018/04/25 06:00 [entrez]
PHST- 2018/04/25 06:00 [pubmed]
PHST- 2018/05/01 06:00 [medline]
AID - 10.1186/s12886-018-0765-7 [doi]
AID - 10.1186/s12886-018-0765-7 [pii]
PST - epublish
SO  - BMC Ophthalmol. 2018 Apr 23;18(1):106. doi: 10.1186/s12886-018-0765-7.