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Case report of the successful treatment of lung injury caused by occupational exposure to methyl chloroformate and literature review.

Abstract The treatment of acute lung injuries caused by the inhalation of methyl chloroformate remains a difficult clinical problem, with a poor prognosis and a high mortality.
PMID
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The toxicity of methyl chloroformate. Demonstrated by a case of poisoning with a fatal course.

Authors

Mayor MeshTerms
Keywords
Journal Title medicine
Publication Year Start




PMID- 29702974
OWN - NLM
STAT- MEDLINE
DCOM- 20180514
LR  - 20180516
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 97
IP  - 17
DP  - 2018 Apr
TI  - Case report of the successful treatment of lung injury caused by occupational
      exposure to methyl chloroformate and literature review.
PG  - e0288
LID - 10.1097/MD.0000000000010288 [doi]
AB  - BACKGROUND: The treatment of acute lung injuries caused by the inhalation of
      methyl chloroformate remains a difficult clinical problem, with a poor prognosis 
      and a high mortality. CASE PRESENTATION: After inhalation injuries from methyl
      chloroformate poisoning, bronchoscopy plays an important role in the diagnosis
      and treatment of patients. A low tidal air volume and earlier application of
      steroids are also essential for successful treatment. The grading of acute
      exposure guideline levels (AEGLs) can direct the selection of a therapeutic
      regimen for patients with methyl chloroformate poisoning. CONCLUSIONS: By
      analyzing the reported acute methyl chloroformate inhalation poisoning cases in
      China during 1989 to 2017, this study aims to value occupational protection in
      production activities, accumulate clinical experiences, and provide guidance for 
      the treatment of such cases in the future.
FAU - Zhao, Jiayi
AU  - Zhao J
AD  - Department of Respiratory and Critical Care Medicine.
FAU - Chai, Rong
AU  - Chai R
AD  - Department of Respiratory and Critical Care Medicine.
FAU - Han, Yiping
AU  - Han Y
AD  - Department of Respiratory and Critical Care Medicine.
FAU - Sheng, Jing
AU  - Sheng J
AD  - Department of Medical Imaging, Changhai Hospital, affiliated to Second Military
      Medical University, Shanghai, P.R. China.
FAU - Bai, Chong
AU  - Bai C
AD  - Department of Respiratory and Critical Care Medicine.
FAU - Huang, Haidong
AU  - Huang H
AD  - Department of Respiratory and Critical Care Medicine.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 0 (Formates)
RN  - RC6VA8OB2N (methyl chloroformate)
SB  - AIM
SB  - IM
MH  - China
MH  - Female
MH  - Formates/*poisoning
MH  - Humans
MH  - Inhalation Exposure/*adverse effects
MH  - Lung Injury/diagnostic imaging/*therapy
MH  - Middle Aged
MH  - Occupational Exposure/*adverse effects
PMC - PMC5944481
EDAT- 2018/04/29 06:00
MHDA- 2018/05/15 06:00
CRDT- 2018/04/29 06:00
PHST- 2018/04/29 06:00 [entrez]
PHST- 2018/04/29 06:00 [pubmed]
PHST- 2018/05/15 06:00 [medline]
AID - 10.1097/MD.0000000000010288 [doi]
AID - 00005792-201804270-00006 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2018 Apr;97(17):e0288. doi: 10.1097/MD.0000000000010288.