PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

Dedifferentiated endometrioid adenocarcinoma with trophoblastic components and elevated serum alfa-fetoprotein: A case report and literature review.

Abstract Dedifferentiated endometrioid adenocarcinoma (DEAC) consisted of a combination of undifferentiated and differentiated carcinoma is more aggressive than other conventional endometrioid adenocarcinomas.
PMID
Related Publications

Endometrial adenocarcinoma with trophoblastic differentiation.

Endometrial carcinoma with yolk sac tumor-like differentiation and elevated serum β-hCG: a case report and literature review.

Uterine endometrioid carcinoma with focal area of choriocarcinomatous differentiation: case report.

Endometrioid carcinoma of the endometrium with choriocarcinomatous differentiation: a case report and review of the literature.

Dedifferentiated endometrioid adenocarcinoma of the uterus: a case report.

Authors

Mayor MeshTerms
Keywords
Journal Title medicine
Publication Year Start




PMID- 29703038
OWN - NLM
STAT- MEDLINE
DCOM- 20180507
LR  - 20180516
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 97
IP  - 17
DP  - 2018 Apr
TI  - Dedifferentiated endometrioid adenocarcinoma with trophoblastic components and
      elevated serum alfa-fetoprotein: A case report and literature review.
PG  - e0551
LID - 10.1097/MD.0000000000010551 [doi]
AB  - RATIONALE: Dedifferentiated endometrioid adenocarcinoma (DEAC) consisted of a
      combination of undifferentiated and differentiated carcinoma is more aggressive
      than other conventional endometrioid adenocarcinomas. PATIENT CONCERNS: A
      33-year-old woman with atypical vaginal bleeding was refereed to our hospital.
      She had an endometrial biopsy in a local clinic which showed differentiated
      endometrioid carcinoma with trophoblastic components. High levels of beta-Human
      chorionic gonadotropin (beta-hCG) and alfa-fetoprotein (AFP) were detected in the
      patient's serum. INTERVENTIONS: The patient underwent total hysterectomy with
      bilateral salpingo-oophorectomy, total omentectomy and systemic pelvic
      lymphadenectomy in our center. DIAGNOSIS: Pathological investigation indicated
      that the tumor had well differentiated and undifferentiated adenocarcinoma as
      well as trophoblastic components. OUTCOMES: Serum beta-hCG and AFP dropped
      significantly after operation. But three weeks later, the patient had developed
      pulmonary metastases and elevation of serum beta-hCG. She died of the disease
      five months after surgery. LESSONS: DEAC with trophoblastic differentiation seems
      to follow an aggressive course with early metastasis and poor clinical prognosis.
      However, due to small number of cases, further studies are necessary.
FAU - Cai, He
AU  - Cai H
AD  - Obstetrics and Gynecology Department, Peking University People's Hospital,
      Beijing, China.
FAU - Zhou, Rong
AU  - Zhou R
FAU - Liang, Wanying
AU  - Liang W
FAU - Wang, Jianliu
AU  - Wang J
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 0 (alpha-Fetoproteins)
SB  - AIM
SB  - IM
MH  - Adult
MH  - Carcinoma, Endometrioid/*blood/*pathology
MH  - Cell Dedifferentiation
MH  - Endometrial Neoplasms/*blood/*pathology
MH  - Fatal Outcome
MH  - Female
MH  - Humans
MH  - Trophoblastic Neoplasms/*blood/*pathology
MH  - alpha-Fetoproteins/*analysis
PMC - PMC5944540
EDAT- 2018/04/29 06:00
MHDA- 2018/05/08 06:00
CRDT- 2018/04/29 06:00
PHST- 2018/04/29 06:00 [entrez]
PHST- 2018/04/29 06:00 [pubmed]
PHST- 2018/05/08 06:00 [medline]
AID - 10.1097/MD.0000000000010551 [doi]
AID - 00005792-201804270-00070 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2018 Apr;97(17):e0551. doi: 10.1097/MD.0000000000010551.