PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.




PMID- 29715133
OWN - NLM
STAT- MEDLINE
DCOM- 20180508
LR  - 20180508
IS  - 1791-7530 (Electronic)
IS  - 0250-7005 (Linking)
VI  - 38
IP  - 5
DP  - 2018 May
TI  - Cytoreductive Nephrectomy in Elderly Patients with Metastatic Renal Cell
      Carcinoma in the Targeted Therapy Era.
PG  - 3013-3018
AB  - BACKGROUND/AIM: The role of cytoreductive nephrectomy (CN) for metastatic renal
      cell cancer (mRCC) is not clearly understood after the approval of targeted
      therapies, particularly in the elderly population. The aim of this study was to
      compare survivals between patients who did and did not receive CN. PATIENTS AND
      METHODS: The SEER-18 database was utilized in order to identify elderly patients 
      with mRCC to compare overall survival (OS) and cancer-specific survival (CSS)
      between patients who did or did not receive CN between February 2006 and 2012.
      Kaplan-Meier curve and log rank test were used to compare OS and CSS between
      these two arms. Cox proportional hazard model was used for multivariate analysis 
      and statistical significance was defined as p</=0.05. RESULTS: There was a
      significant survival benefit for those who received CN compared to those who did 
      not receive CN (median OS: 18 months vs. 4 months, p<0.001; median CSS: 21 months
      vs. 5 months, p<0.001). CONCLUSION: CN offered significant survival benefit, even
      in elderly patients with metastatic renal cell cancer.
CI  - Copyright(c) 2018, International Institute of Anticancer Research (Dr. George J. 
      Delinasios), All rights reserved.
FAU - Uprety, Dipesh
AU  - Uprety D
AD  - Department of Medical Oncology, Gundersen Health System, La Crosse, WI, U.S.A.
      [email protected]
FAU - Bista, Amir
AU  - Bista A
AD  - Department of Medical Oncology, Gundersen Health System, La Crosse, WI, U.S.A.
FAU - Smith, Angela L
AU  - Smith AL
AD  - Division of Medical Research, Gundersen Lutheran Medical Foundation, La Crosse,
      WI, U.S.A.
FAU - Vallatharasu, Yazhini
AU  - Vallatharasu Y
AD  - Department of Medical Oncology, Gundersen Health System, La Crosse, WI, U.S.A.
FAU - Marinier, David E
AU  - Marinier DE
AD  - Department of Medical Oncology, Gundersen Health System, La Crosse, WI, U.S.A.
LA  - eng
PT  - Journal Article
PL  - Greece
TA  - Anticancer Res
JT  - Anticancer research
JID - 8102988
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Carcinoma, Renal Cell/mortality/*surgery
MH  - Case-Control Studies
MH  - Female
MH  - Humans
MH  - Kaplan-Meier Estimate
MH  - Kidney Neoplasms/mortality/*surgery
MH  - Male
MH  - Nephrectomy
MH  - Proportional Hazards Models
MH  - Retrospective Studies
MH  - SEER Program
OTO - NOTNLM
OT  - *Cytoreductive nephrectomy
OT  - *elderly
OT  - *renal cell carcinoma
OT  - *targeted era
EDAT- 2018/05/02 06:00
MHDA- 2018/05/09 06:00
CRDT- 2018/05/02 06:00
PHST- 2018/03/15 00:00 [received]
PHST- 2018/03/27 00:00 [revised]
PHST- 2018/03/28 00:00 [accepted]
PHST- 2018/05/02 06:00 [entrez]
PHST- 2018/05/02 06:00 [pubmed]
PHST- 2018/05/09 06:00 [medline]
AID - 38/5/3013 [pii]
AID - 10.21873/anticanres.12555 [doi]
PST - ppublish
SO  - Anticancer Res. 2018 May;38(5):3013-3018. doi: 10.21873/anticanres.12555.