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Changes of corneal high-order aberrations after femtosecond laser-assisted in situ keratomileusis.

Abstract Femtosecond laser-assisted in situ keratomileusis (FS-LASIK) has gained widespread popularity as a safe, effective and predictable treatment for correcting myopia and myopic astigmatism.However, complications such as biomechanical changes, structural weakness, dry eye and induction of high-order aberrations (HOAs) have been associated with FS laser excision. The induction of HOAs has been reported to reduce quality of vision, leading to increased glare, halos, starburst and deterioration of contrast function corneal HOAs play a significant role in whole-eye aberration. Thus, it is necessary to investigate the changes of corneal high-order aberrations after FS-LASIK.
PMID
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Authors

Mayor MeshTerms

Visual Acuity

Keywords
Journal Title medicine
Publication Year Start




PMID- 29718869
OWN - NLM
STAT- MEDLINE
DCOM- 20180508
LR  - 20180508
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 97
IP  - 18
DP  - 2018 May
TI  - Changes of corneal high-order aberrations after femtosecond laser-assisted in
      situ keratomileusis.
PG  - e0618
LID - 10.1097/MD.0000000000010618 [doi]
AB  - BACKGROUND: Femtosecond laser-assisted in situ keratomileusis (FS-LASIK) has
      gained widespread popularity as a safe, effective and predictable treatment for
      correcting myopia and myopic astigmatism.However, complications such as
      biomechanical changes, structural weakness, dry eye and induction of high-order
      aberrations (HOAs) have been associated with FS laser excision. The induction of 
      HOAs has been reported to reduce quality of vision, leading to increased glare,
      halos, starburst and deterioration of contrast function corneal HOAs play a
      significant role in whole-eye aberration. Thus, it is necessary to investigate
      the changes of corneal high-order aberrations after FS-LASIK. METHODS: One
      hundred thirty-four eyes from 68 consecutive patients with myopia or myopic
      astigmatism were enrolled in this study. Corneal topography and visual acuity
      were measured preoperatively and at 1, 3, 6, and 12 months after FS-LASIK.
      Wavefront errors from the whole cornea, anterior cornea, and posterior cornea
      were measured by Pentacam. RESULTS: Corneal aberrations on the posterior surface 
      were less affected by FS-LASIK compared with those on the anterior surface and
      the whole cornea. The high-order aberrations (HOAs) on the whole and anterior
      corneal surfaces increased significantly at 1 month after surgery (P = .000, P = 
      .000), while HOAs on the posterior surface did not significantly change (P =
      1.000). The spherical aberration on the whole corneal and anterior corneal
      surfaces were significantly increased at 1 and 3 months postoperatively (P = .000
      and P = .000, respectively), along with the vertical coma on the whole and
      anterior corneal surfaces at 1 and 3 months (P = .000 and P = .000,
      respectively). There was no significant difference in horizontal coma or trefoil 
      on the whole, anterior and posterior corneal surfaces after surgery compared with
      preoperatively (all P = 1.000). CONCLUSION: After FS-LASIK changes in corneal
      aberration occurred mainly on the anterior surface, which may have a significant 
      effect on visual quality.
FAU - Wang, Jing
AU  - Wang J
AD  - Department of Ophthalmology, the Second Affiliated Hospital of Anhui Medical
      University, Hefei, P.R. China.
FAU - Ren, Yanlin
AU  - Ren Y
FAU - Liang, Kun
AU  - Liang K
FAU - Jiang, Zhengxuan
AU  - Jiang Z
FAU - Tao, Liming
AU  - Tao L
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - AIM
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Astigmatism/*surgery
MH  - Cornea/*pathology
MH  - Female
MH  - Humans
MH  - Keratomileusis, Laser In Situ/*adverse effects
MH  - Male
MH  - Myopia/*surgery
MH  - Retrospective Studies
MH  - *Visual Acuity
MH  - Young Adult
EDAT- 2018/05/03 06:00
MHDA- 2018/05/09 06:00
CRDT- 2018/05/03 06:00
PHST- 2018/05/03 06:00 [entrez]
PHST- 2018/05/03 06:00 [pubmed]
PHST- 2018/05/09 06:00 [medline]
AID - 10.1097/MD.0000000000010618 [doi]
AID - 00005792-201805040-00037 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2018 May;97(18):e0618. doi: 10.1097/MD.0000000000010618.