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PMID- 29742697
DCOM- 20180515
LR  - 20180515
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 97
IP  - 19
DP  - 2018 May
TI  - Giant malignant pheochromocytoma in an elderly patient: A case report.
PG  - e0614
LID - 10.1097/MD.0000000000010614 [doi]
AB  - RATIONALE: Malignant pheochromocytoma is a rare disease and surgical resection is
      the only curative treatment. PATIENT CONCERNS: An 81-year-old man of Chinese
      ethnicity was found to have a giant retroperitoneal tumor. DIAGNOSES: B-scan
      ultrasonography and CT scan presented a mass above the left kidney, measuring
      13.5 x 10 .6 x 9.8 cm. Subsequent analysis of 24-h urinary catecholamines and
      vanillylmandelic acid, as well as of blood catecholamines and blood cortisol,
      showed no elevated levels. INTERVENTIONS: The patient was treated with surgery.
      OUTCOMES: The result from immunohistochemical staining confirmed the presence of 
      malignant pheochromocytoma. After three months follow-up, the blood pressure and 
      serum potassium were all within normal limits, no post-operative complications,
      no tumor recurrence and metastasis were found. LESSONS: This is the oldest
      patient known to have histologic documentation of this disease. Giant malignant
      pheochromocytomas are rare entities requiring clinical suspicion coupled with
      strategic diagnostic evaluation to confirm the diagnosis, personalized
      therapeutic treatment is required, particularly among elderly population.
FAU - Ma, Chengquan
AU  - Ma C
AD  - Department of Urology, Tianjin Nankai Hospital.
FAU - Sun, Erlin
AU  - Sun E
AD  - Tianjin Institute of Urology, The 2nd Hospital of Tianjin Medical University.
FAU - Lu, Bingxin
AU  - Lu B
AD  - Department of Urology, Tianjin Nankai Hospital, Tianjin, China.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 0 (Vasodilator Agents)
RN  - 0TTZ664R7Z (Phenoxybenzamine)
SB  - IM
MH  - *Adrenal Gland Neoplasms/complications/pathology/physiopathology/surgery
MH  - Adrenalectomy/*methods
MH  - Aged, 80 and over
MH  - Humans
MH  - *Hypertension/diagnosis/etiology/prevention & control
MH  - Intraoperative Complications/*prevention & control
MH  - Male
MH  - Neoplasm Staging
MH  - Operative Time
MH  - Phenoxybenzamine/*administration & dosage
MH  - *Pheochromocytoma/complications/pathology/physiopathology/surgery
MH  - Preoperative Care/methods
MH  - Tomography, X-Ray Computed/methods
MH  - Treatment Outcome
MH  - Tumor Burden
MH  - Ultrasonography/methods
MH  - Vasodilator Agents/administration & dosage
EDAT- 2018/05/10 06:00
MHDA- 2018/05/16 06:00
CRDT- 2018/05/10 06:00
PHST- 2018/05/10 06:00 [entrez]
PHST- 2018/05/10 06:00 [pubmed]
PHST- 2018/05/16 06:00 [medline]
AID - 10.1097/MD.0000000000010614 [doi]
AID - 00005792-201805110-00016 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2018 May;97(19):e0614. doi: 10.1097/MD.0000000000010614.