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Pre-hospitalization, hospitalization, and post-hospitalization costs of patients with neurocysticercosis treated at the Instituto Nacional de Neurologia y Neurocirugia (INNN) in Mexico City, Mexico.

Abstract The objective of this study was to estimate the direct costs associated with the diagnosis and treatment of neurocysticercosis (NCC) during pre-hospitalization, hospitalization, and post-hospitalization periods for 108 NCC patients treated at the Instituto Nacional de Neurologia y Neurocirugia (INNN) in Mexico City, Mexico. Information on clinical manifestations, diagnostic tests, hospitalizations, surgical procedures, prescription medication, and other treatments was collected via medical chart reviews. Uncertain values for costs and frequency of treatments were imputed using bootstrap techniques. The average per-patient pre-hospitalization and hospitalization costs were US$ 257 (95% CI: 185 - 329) and US$ 2,576 (95% CI: 2,244 - 2,908), respectively. Post-hospitalization costs tended to decrease over time, with estimates for the first five years post-hospitalization of US$ 475 (95% CI: 423 - 527), US$ 228 (95% CI: 167 - 288), US$ 157 (95% CI: 111 - 202), US$ 150 (95% CI: 106 - 204), and US$ 91 (95% CI: 27 - 154), respectively. NCC results in a significant economic burden for patients requiring hospitalization, with this burden continuing years post-hospitalization.
PMID
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Authors

Mayor MeshTerms

Cost of Illness

Keywords
Journal Title revista do instituto de medicina tropical de sao paulo
Publication Year Start




PMID- 29846471
OWN - NLM
STAT- MEDLINE
DCOM- 20180605
LR  - 20180606
IS  - 1678-9946 (Electronic)
IS  - 0036-4665 (Linking)
VI  - 60
DP  - 2018
TI  - Pre-hospitalization, hospitalization, and post-hospitalization costs of patients 
      with neurocysticercosis treated at the Instituto Nacional de Neurologia y
      Neurocirugia (INNN) in Mexico City, Mexico.
PG  - e20
LID - S0036-46652018005000211 [pii]
LID - 10.1590/s1678-9946201860020 [doi]
AB  - The objective of this study was to estimate the direct costs associated with the 
      diagnosis and treatment of neurocysticercosis (NCC) during pre-hospitalization,
      hospitalization, and post-hospitalization periods for 108 NCC patients treated at
      the Instituto Nacional de Neurologia y Neurocirugia (INNN) in Mexico City,
      Mexico. Information on clinical manifestations, diagnostic tests,
      hospitalizations, surgical procedures, prescription medication, and other
      treatments was collected via medical chart reviews. Uncertain values for costs
      and frequency of treatments were imputed using bootstrap techniques. The average 
      per-patient pre-hospitalization and hospitalization costs were US$ 257 (95% CI:
      185 - 329) and US$ 2,576 (95% CI: 2,244 - 2,908), respectively.
      Post-hospitalization costs tended to decrease over time, with estimates for the
      first five years post-hospitalization of US$ 475 (95% CI: 423 - 527), US$ 228
      (95% CI: 167 - 288), US$ 157 (95% CI: 111 - 202), US$ 150 (95% CI: 106 - 204),
      and US$ 91 (95% CI: 27 - 154), respectively. NCC results in a significant
      economic burden for patients requiring hospitalization, with this burden
      continuing years post-hospitalization.
FAU - Bhattarai, Rachana
AU  - Bhattarai R
AD  - Department of Veterinary Integrative Biosciences, Texas A&M University College of
      Veterinary Medicine & Biomedical Sciences, College Station, Texas, United States.
FAU - Carabin, Helene
AU  - Carabin H
AD  - Department of Biostatistics and Epidemiology, University of Oklahoma Health
      Sciences Center, Oklahoma City,, Oklahoma, United States.
FAU - Flores-Rivera, Jose
AU  - Flores-Rivera J
AD  - Instituto Nacional de Neurologia y Neurocirugia, Laboratorio Clinico de
      Enfemedades Neurodegeneraivas, Mexico, DF, Mexico.
FAU - Corona, Teresa
AU  - Corona T
AD  - Instituto Nacional de Neurologia y Neurocirugia, Laboratorio Clinico de
      Enfemedades Neurodegeneraivas, Mexico, DF, Mexico.
FAU - Proano, Jefferson V
AU  - Proano JV
AD  - Instituto Mexicano del Seguro Social, Centro Medico Nacional Siglo XXI, Hospital 
      de Especialidades, Mexico, DF, Mexico.
FAU - Flisser, Ana
AU  - Flisser A
AD  - Departamento de Microbiologia y Parasitologia, Facultad de Medicina, Universidad 
      Nacional Autonoma de Mexico, Mexico, DF, Mexico.
FAU - Budke, Christine M
AU  - Budke CM
AD  - Department of Veterinary Integrative Biosciences, Texas A&M University College of
      Veterinary Medicine & Biomedical Sciences, College Station, Texas, United States.
LA  - eng
PT  - Journal Article
DEP - 20180528
PL  - Brazil
TA  - Rev Inst Med Trop Sao Paulo
JT  - Revista do Instituto de Medicina Tropical de Sao Paulo
JID - 7507484
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - *Cost of Illness
MH  - Female
MH  - Health Care Costs/*statistics & numerical data
MH  - Hospitalization/*economics
MH  - Humans
MH  - Male
MH  - Mexico
MH  - Middle Aged
MH  - Neurocysticercosis/*economics
MH  - Referral and Consultation/economics
MH  - Young Adult
PMC - PMC5975722
EDAT- 2018/05/31 06:00
MHDA- 2018/06/06 06:00
CRDT- 2018/05/31 06:00
PHST- 2017/11/24 00:00 [received]
PHST- 2018/03/01 00:00 [accepted]
PHST- 2018/05/31 06:00 [entrez]
PHST- 2018/05/31 06:00 [pubmed]
PHST- 2018/06/06 06:00 [medline]
AID - S0036-46652018005000211 [pii]
AID - 10.1590/s1678-9946201860020 [doi]
PST - ppublish
SO  - Rev Inst Med Trop Sao Paulo. 2018;60:e20. doi: 10.1590/s1678-9946201860020. Epub 
      2018 May 28.