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Daily Setup Accuracy, Side-effects and Quality of Life During and After Prone Positioned Prostate Radiotherapy.

Abstract Exposure of organs at risk with prostate radiotherapy (RT) is lower in the prone position. This study is a prospective evaluation of setup accuracy, side-effects, and quality of life (QOL) during and after prone positioned RT.
PMID
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Authors

Mayor MeshTerms

Prone Position

Quality of Life

Keywords

IMRT

Prostate cancer

belly board (BB)

daily setup accuracy

prone

quality of life and side-effects

Journal Title anticancer research
Publication Year Start




PMID- 29848730
OWN - NLM
STAT- MEDLINE
DCOM- 20180611
LR  - 20180611
IS  - 1791-7530 (Electronic)
IS  - 0250-7005 (Linking)
VI  - 38
IP  - 6
DP  - 2018 Jun
TI  - Daily Setup Accuracy, Side-effects and Quality of Life During and After Prone
      Positioned Prostate Radiotherapy.
PG  - 3699-3705
LID - 10.21873/anticanres.12648 [doi]
AB  - BACKGROUND/AIM: Exposure of organs at risk with prostate radiotherapy (RT) is
      lower in the prone position. This study is a prospective evaluation of setup
      accuracy, side-effects, and quality of life (QOL) during and after prone
      positioned RT. PATIENTS AND METHODS: Image-guided (IG) intensity-modulated (IM)
      RT was administered in prone position on belly-board to 55 high-risk prostate
      cancer (PC) patients. Rectum diameters were measured in two areas of the
      symphysis at the beginning of RT and during it. Side-effects, QOL, and prostate
      specific symptoms (PSS) were evaluated. RESULTS: Setup accuracy was similar to
      that reported in the literature. In the upper area of symphysis rectal diameters 
      were significantly changed during treatment, but in the prostate region, no
      difference was detected. No change was detected in patients' QOL and PSS during
      treatment, but after RT, they improved. CONCLUSION: Prone positioned IG-IMRT is
      feasible with tolerable side-effects for high-risk PC patients. Changes in QOL
      and PSS are insignificant during RT, while improvement after RT suggests a rapid 
      recovery.
CI  - Copyright(c) 2018, International Institute of Anticancer Research (Dr. George J. 
      Delinasios), All rights reserved.
FAU - Varga, Linda
AU  - Varga L
AD  - Department of Oncotherapy, University of Szeged, Szeged, Hungary.
FAU - Koszo, Renata Lilla
AU  - Koszo RL
AD  - Department of Oncotherapy, University of Szeged, Szeged, Hungary.
FAU - Fodor, Emese
AU  - Fodor E
AD  - Department of Oncotherapy, University of Szeged, Szeged, Hungary.
FAU - Cserhati, Adrienne
AU  - Cserhati A
AD  - Department of Oncotherapy, University of Szeged, Szeged, Hungary.
FAU - Varga, Zoltan
AU  - Varga Z
AD  - Department of Oncotherapy, University of Szeged, Szeged, Hungary.
FAU - Darazs, Barbara
AU  - Darazs B
AD  - Department of Oncotherapy, University of Szeged, Szeged, Hungary.
FAU - Kahan, Zsuzsanna
AU  - Kahan Z
AD  - Department of Oncotherapy, University of Szeged, Szeged, Hungary.
FAU - Hideghety, Katalin
AU  - Hideghety K
AD  - Department of Oncotherapy, University of Szeged, Szeged, Hungary.
FAU - Borzasi, Emoke
AU  - Borzasi E
AD  - Department of Oncotherapy, University of Szeged, Szeged, Hungary.
FAU - Szabo, Dorottya
AU  - Szabo D
AD  - Department of Oncotherapy, University of Szeged, Szeged, Hungary.
FAU - Mullner, Kitti
AU  - Mullner K
AD  - Department of Oncotherapy, University of Szeged, Szeged, Hungary.
FAU - Maraz, Aniko
AU  - Maraz A
AD  - Department of Oncotherapy, University of Szeged, Szeged, Hungary
      [email protected]
LA  - eng
PT  - Journal Article
PL  - Greece
TA  - Anticancer Res
JT  - Anticancer research
JID - 8102988
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Outcome Assessment (Health Care)
MH  - *Prone Position
MH  - Prospective Studies
MH  - Prostatic Neoplasms/*radiotherapy
MH  - *Quality of Life
MH  - Radiotherapy Planning, Computer-Assisted/adverse effects/*methods
MH  - Radiotherapy, Intensity-Modulated/adverse effects/*methods
MH  - Rectum/diagnostic imaging/radiation effects
MH  - Risk Factors
MH  - Tomography, X-Ray Computed
OTO - NOTNLM
OT  - IMRT
OT  - Prostate cancer
OT  - belly board (BB)
OT  - daily setup accuracy
OT  - prone
OT  - quality of life and side-effects
EDAT- 2018/06/01 06:00
MHDA- 2018/06/12 06:00
CRDT- 2018/06/01 06:00
PHST- 2018/03/19 00:00 [received]
PHST- 2018/04/19 00:00 [revised]
PHST- 2018/04/20 00:00 [accepted]
PHST- 2018/06/01 06:00 [entrez]
PHST- 2018/06/01 06:00 [pubmed]
PHST- 2018/06/12 06:00 [medline]
AID - 38/6/3699 [pii]
AID - 10.21873/anticanres.12648 [doi]
PST - ppublish
SO  - Anticancer Res. 2018 Jun;38(6):3699-3705. doi: 10.21873/anticanres.12648.