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Acute exacerbation of staphylococcal catarrhal infiltration associated with treatment for Pseudomonas aeruginosa keratitis: A case report.

Abstract Simultaneous presentation of peripheral infiltrates, which can be easily misidentified as satellite lesions, is rarely observed in patients with acute infectious keratitis.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title medicine
Publication Year Start




PMID- 29851781
OWN - NLM
STAT- MEDLINE
DCOM- 20180608
LR  - 20180608
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 97
IP  - 22
DP  - 2018 Jun
TI  - Acute exacerbation of staphylococcal catarrhal infiltration associated with
      treatment for Pseudomonas aeruginosa keratitis: A case report.
PG  - e10753
LID - 10.1097/MD.0000000000010753 [doi]
AB  - RATIONALE: Simultaneous presentation of peripheral infiltrates, which can be
      easily misidentified as satellite lesions, is rarely observed in patients with
      acute infectious keratitis. PATIENT CONCERNS: A 70-year-old woman was referred to
      our clinic due to acute mucopurulent keratitis following application of a
      therapeutic soft contact lens for the treatment of epithelial defects caused by
      entrance of soil foreign bodies into the eye. The patient was diagnosed with
      Pseudomonas keratitis, following which she was treated with alternating
      administration of fourth-generation fluoroquinolone (Vigamox) and 5% fortified
      ceftazidime eyedrops every 2 hours. Although infectious keratitis rapidly
      improved, discrete catarrhal infiltrates at the corneolimbal junction (10- to
      2-o'clock and 7- to 8-o'clock positions) were rapidly aggravated, forming
      bead-like stromal pustules inversely proportional to the extent of Pseudomonas
      keratitis. DIAGNOSIS: Acute exacerbation of staphylococcal catarrhal infiltration
      associated with treatment for Pseudomonas aeruginosa keratitis. INTERVENTIONS:
      Addition of 1% prednisone acetate eyedrops (Pred Forte) four times per day.
      OUTCOMES: Dramatic improvement was observed at the sites of catarrhal
      infiltration without recurrence of infectious keratitis. LESSONS: Clinicians
      should thus remain aware of the risk for co-occurring non-infectious,
      immune-related keratitis, as treatment for infectious keratitis may induce
      significant aggravation of non-infectious keratitis.
FAU - Bang, Seung Pil
AU  - Bang SP
AD  - Department of Ophthalmology, Dongsan Medical Center, Keimyung University School
      of Medicine, Daegu, Korea.
FAU - Jun, Jong Hwa
AU  - Jun JH
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Fluoroquinolones)
RN  - 0 (Glucocorticoids)
RN  - 9M416Z9QNR (Ceftazidime)
RN  - VB0R961HZT (Prednisone)
SB  - AIM
SB  - IM
MH  - Acute Disease
MH  - Aged
MH  - Anti-Bacterial Agents/therapeutic use
MH  - Ceftazidime/administration & dosage/therapeutic use
MH  - Contact Lenses, Hydrophilic/adverse effects/microbiology
MH  - Disease Progression
MH  - Eye Infections, Bacterial/complications/diagnosis/drug therapy/microbiology
MH  - Female
MH  - Fluoroquinolones/administration & dosage/therapeutic use
MH  - Glucocorticoids/therapeutic use
MH  - Humans
MH  - Keratitis/diagnosis/drug therapy/*microbiology
MH  - Prednisone/administration & dosage/therapeutic use
MH  - Pseudomonas Infections/*drug therapy/microbiology
MH  - Pseudomonas aeruginosa/*isolation & purification
MH  - Staphylococcal Infections/complications/diagnosis/drug therapy/microbiology
MH  - Staphylococcus/*isolation & purification
MH  - Treatment Outcome
EDAT- 2018/06/01 06:00
MHDA- 2018/06/09 06:00
CRDT- 2018/06/01 06:00
PHST- 2018/06/01 06:00 [entrez]
PHST- 2018/06/01 06:00 [pubmed]
PHST- 2018/06/09 06:00 [medline]
AID - 10.1097/MD.0000000000010753 [doi]
AID - 00005792-201806010-00009 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2018 Jun;97(22):e10753. doi: 10.1097/MD.0000000000010753.