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Perianal ulcerative skin tuberculosis: A case report.

Abstract Ulcerative skin tuberculosis (TB) is a rare form of extrapulmonary TB.
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Mayor MeshTerms
Journal Title medicine
Publication Year Start

PMID- 29851791
DCOM- 20180608
LR  - 20180608
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 97
IP  - 22
DP  - 2018 Jun
TI  - Perianal ulcerative skin tuberculosis: A case report.
PG  - e10836
LID - 10.1097/MD.0000000000010836 [doi]
AB  - RATIONALE: Ulcerative skin tuberculosis (TB) is a rare form of extrapulmonary TB.
      CASE REPORT: We present a case of a 65-year-old patient with perianal ulcer,
      which had been present for 1 year. Anamnesis revealed he had been persistently
      coughing for the same period of time. Histological examination of perianal skin
      showed necrotizing granulomatous lesions, acid-fast staining in sputum samples
      was ++++, TB antibody in the blood was positive, TB DNA test was positive, and
      chest scan that showed secondary pulmonary TB accompanied by possible pulmonary
      cavity formation in the 2 upper lungs. INTERVENTIONS: Anti-TB therapy with
      isoniazid, rifampicin, ethambutol, and pyrazinamide for 6 months. The skin ulcer 
      completely healed after 6 months. CONCLUSION: TB should be suspected for
      nonhealing ulcers. Pertinent studies should be done early during the lesion;
      finally, TB treatment should be initiated immediately after diagnosis is made.
FAU - Wu, Shaofang
AU  - Wu S
AD  - Department of Pathology.
FAU - Wang, Wu
AU  - Wang W
AD  - Department of Anesthesiology, Lishui Central Hospital, Lishui, Zhejiang, China.
FAU - Chen, Huan
AU  - Chen H
AD  - Department of Pathology.
FAU - Xiong, Wen
AU  - Xiong W
AD  - Department of Pathology.
FAU - Song, Xin
AU  - Song X
AD  - Department of Pathology.
FAU - Yu, Xinmin
AU  - Yu X
AD  - Department of Pathology.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 0 (Antitubercular Agents)
RN  - 2KNI5N06TI (Pyrazinamide)
RN  - 8G167061QZ (Ethambutol)
RN  - V83O1VOZ8L (Isoniazid)
RN  - VJT6J7R4TR (Rifampin)
SB  - IM
MH  - Aged
MH  - Antitubercular Agents/therapeutic use
MH  - Ethambutol/administration & dosage/therapeutic use
MH  - Fissure in Ano/drug therapy/microbiology/*pathology
MH  - Humans
MH  - Isoniazid/administration & dosage/therapeutic use
MH  - Male
MH  - Mycobacterium tuberculosis/genetics/isolation & purification
MH  - Pyrazinamide/administration & dosage/therapeutic use
MH  - Rifampin/administration & dosage/therapeutic use
MH  - Sputum/immunology
MH  - Tomography, X-Ray Computed/methods
MH  - Treatment Outcome
MH  - Tuberculosis, Cutaneous/drug therapy/microbiology/*pathology
MH  - Tuberculosis, Pulmonary/complications/*diagnostic imaging/drug therapy/pathology
EDAT- 2018/06/01 06:00
MHDA- 2018/06/09 06:00
CRDT- 2018/06/01 06:00
PHST- 2018/06/01 06:00 [entrez]
PHST- 2018/06/01 06:00 [pubmed]
PHST- 2018/06/09 06:00 [medline]
AID - 10.1097/MD.0000000000010836 [doi]
AID - 00005792-201806010-00019 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2018 Jun;97(22):e10836. doi: 10.1097/MD.0000000000010836.